Error codes “0x80070643” or “0x643” occur when you install the .NET Framework updates
When you try to install updates for the .NET Framework by using Windows Update, Microsoft Update, or an update to the .NET Framework, you may receive an error that has one of the following error codes:

Error code: 0x80070643
Error code: 0x643


This issue may occur if the MSI software update registration has become corrupted, or if the .NET installation on the computer has become corrupted.

1.       Add or Remove Programs.
2.       Click Microsoft .NET Framework 4 Client Profile in the list of installed programs, and then click Change/Remove.
3.       Select Repair .NET Framework 4 Client Profile to its original state, and then click Next.
4.       When the repair is complete, click Finish.
5.       Click Restart Now.
6.       After the computer restarts and you log on to Windows, click Start, type Windows Update in the Search box, and then click Windows Update.
7.       Click Check for updates. After the scan is complete, click Install Windows Updates, and then follow the instructions.
.NET Framework 1.1, 2.0, 3.0, 3.5
Follow these steps if you are running Windows 8:
1.       Swipe in from the right edge of the screen, and then tap Search.

Note If you're using a mouse, point to the upper-right corner of the screen, move the mouse pointer down, and then click Search.
2.       Tap or click Settings, and then enter the name of the app you want to find.
3.       Tap or click Uninstall a program
4.       Tap or click Turn Windows features on or off
5.       Tap or click to unselect the box for .Net framework 3.5 (includes .Net2.0 and 3.0)
6.       Tap or click OK and click Close when the uninstall is complete.
7.       Tap or click to close the Uninstall a program window.

Follow these steps if you are running WindowsXP, Windows Vista and Windows 7:

To repair the .NET Framework 1.1, 2.0, 3.0, 3.5, use the .NET Framework Cleanup Tool to uninstall multiple versions of the .NET Framework, and then reinstall the components.

To do this, follow these steps:
1.       Visit the following blog post:
2.       Download from the following site:
3.       When you are prompted, click Open, and then click Extract Now.
4.       In the files that you extracted, double-click cleanup_tool.exe.
If you are prompted for an administrator password or for confirmation, provide the password, and then click Continue.
5.    In the Do you want to run the .NET Framework Setup Cleanup Utility? message, click Yes.
Note This tool may be in English only, but it also works for other language versions of Windows.
6.       Click Yes to accept the license agreement.
7.    In the Product to cleanup window, click the list, select .NET Framework - All Versions, and then click Cleanup Now.
Note The cleanup tool does not let you remove the .NET Framework 2.0 in Windows Vista or later versions of Windows because the .NET Framework is installed as an operating system component.
8.       After the .NET Framework is removed, restart the computer.
9.       Download and install the following components:
.NET Framework 1.1
Microsoft .NET Framework Version 1.1 Redistributable Package

.NET Framework 1.1 Service Pack 1 (SP1)
Microsoft .NET Framework 1.1 Service Pack 1

.NET Framework 3.5 SP1 (this will also install the .NET Framework 2.0 SP2 and the .NET Framework 3.0 SP2)
10.    Restart the computer.

11.    Visit Windows Update again, and then check for and install updates.

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